Target List
Toll-Like Receptor (TLR) Signaling
Receptors & Chaperones
CTSB, CTSV, CTSS, TLR2, TLR3, TLR7, TLR8, TLR9
Signaling Downstream of Toll-Like Receptors
BCL2, JUN, CHUK (IKKα), CSF2 (GM-CSF), FOS, IKBKB, IRAK1, IRF3, IRF5, IRF7, MAP2K1 (MEK1), MAP3K7 (TAK1), MAP3K8, MAPK1 (ERK2), MAPK1 (ERK2), MAPK14 (p38ALPHA), MAPK14 (p38ALPHA), MAPK3 (ERK1), MAPK3 (ERK1), MAPK8, MYD88, NFKB1, NFKBIA (IκBα, MAD3), PELI1, RELA, RIPK1, SPP1, TBK1, TICAM2, TNF, TRAF3, TRAF6
Toll-Like Receptor Signaling Responsive Genes
CCL3L1 (CCL3), CCL4 (MIP-1B), CCL5 (RANTES), CD40, CD80, CD86, CXCL10 (INP10), CXCL11 (I-TAC, IP-9), CXCR4, CXCL9 (MIG), IFNB1, IL12A, IL12B, IL15, IL1B, IL23A, IL6
NOD-Like Receptor Signaling
Receptors & Signaling Molecules
CASP1, HSP90AA1, MEFV, NLRP3, NOD2, OAS2, PSTPIP1, LOC100522011, SUGT1
NOD-Like Receptor Signaling Responsive Genes
IL1B, IL18
RIG-I-Like Receptor Signaling
Receptors & Chaperones
TKFC, DDX58, DHX58, IFIH1, ISG15 (G1P2), CYLD, LOC100737114
Signaling Downstream of RIG-I-Like Receptors
ATG5, AZI2, BCL2, CASP10, CASP8 (FLICE), CHUK (IKKα), DDX3X, IKBKB, IRF3, IRF7, MAP3K1 (MEKK1), MAP3K7 (TAK1), MAP3K8, MAPK14 (p38ALPHA), MAPK14 (p38ALPHA), MAPK8, MAVS, NFKB1, NFKBIA (IκBα, MAD3), PIN1, RELA, RIPK1, TBK1, TNF, LOC100620340, TRAF3, TRAF6
RIG-I-Like Receptor Signaling Responsive Genes
CXCL10 (INP10), IFNB1, IL12A, IL12B, CXCL8
Type I Interferon Signaling & Response
Type I Interferon Signaling
IFNAR1, IFNB1, STAT1
Interferon Responsive Genes
CSF2 (GM-CSF), CXCR4, IL15, IL23A, ISG15 (G1P2), MX1, TLR3