Target List
Cytokines & Receptors
CCL5 (RANTES)CCR3CCR4CCR5CCR6CXCR3IL10IL12BIL12RB2IL13IL13RA1IL17AIL17REIL18IL18R1 (IL18RA)IL18RAPIL1R2IL1RL1IL2IL21IL2RAIL4IL4R (CD124)IL5IL6IL6RIL9TNF
T Helper 1 Subtype Markers
CCR5HAVCR2IGSF6IL12BIL18IRF1SOCS1SOCS5TLR4TLR6TNF
T Helper 2 Subtype Markers
CCL5 (RANTES)CCR3CCR4CEBPBICOSIL13RA1IL4R (CD124)JAK1NFATC2NFATC2IPPCGF2PTGDR2
Transcription Factors
CEBPBFOSL1FOXP3GATA3GATA4HOXA10HOXA11HOXA3ID2IRF4IRF8LOC100156637 (RORA)LOC100520325 (ZEB1)MAFNFATC2NFATC2IPNR4A3RELRELBRORCRUNX1 (AML1)STAT1STAT4STAT6TOXZBTB7B
Epigenetically Regulated Genes
Th1 Cells
IFNGIL12RB2IL18R1 (IL18RA)IL18RAPFASLG (TNFSF6)TBX21
Th2 Cells
ASB2 (ASB2)GATA3IL13IL1RL1IL4IL5PPARG
Th17 Cells
IL17AIL17REIL21LOC100156637 (RORA)RORC
Inducible & Natural Regulatory T (iTreg & nTreg) Cells
CCR6FOSL1FOXP3IKZF2IL9IRF4IRF8MYBNR4A3RELRELBTGIF1TNFSF11
Conventional Versus Regulatory T-Cells
CACNA1FCHD7FOXP3GATA4HOPXHOXA10HOXA11HOXA3ID2IKZF2IL1R2IL2RAKIF2CLOC100520045 (FCMR)LOC100520325 (ZEB1)LRRC32PKD2TNFRSF9TP53INP1UTS2