Target List
Necrosis
Regulation of Necrosis
fasfaslgripk1l (RIPK1)slc25a4tnfatnfb
TNF-Induced Necrosis
bmf1bmf2ccdc103commd4cylda (CYLD)defbl1dennd4adpysl4eif5bfoxi1grb2a (GRB2)grb2b (GRB2)hspbap1jph3kcnip1a (KCNIP1)kcnip1b (KCNIP1)magparp2rab25a (RAB25)spata2sycp2tmem57a (TMEM57)txnl4b
Other Necrosis Genes
cd40faddmgea5parp1ppiaa (PPIA)ripk1l (RIPK1)ripk3sp1tmem123
Potential Necrosis Genes
RIPK1 Interactors
fusnfkb1ripk1l (RIPK1)ripk2ripk3
RIPK3 Interactors
glud1a (GLUD1)glud1b (GLUD1)glula (GLUL)phtf2pyglripk1l (RIPK1)
PARP1 Interactors
capn1a (CAPN1)capn1b (CAPN1)capn2l (CAPN2)capn3acapn5a (CAPN5)capn5b (CAPN5)capn7capns1a (CAPNS1)capns1b (CAPNS1)ppid
Death Domain Receptors
fastnfrsf18tnfrsf19tnfrsf1atnfrsf21
Death Receptor Signaling
bida (BID)birc2casp8ap2cylda (CYLD)faddfaf1fem1bikbkgmaddmyd88ngfa (NGF)ngfbparp1pidd1ripk1l (RIPK1)tnfrsf17tnfrsf1btraddtraf2a
Apoptosis
Pro-Apoptotic
aifm1baxa (BAX)baxb (BAX)bida (BID)bmf1bmf2bnip3lb (BNIP3L)casp8ap2faddfaf1fasfaslgfem1bikbkgmaddpidd1ripk1l (RIPK1)ripk2ripk3tnfatnfbtnfsf10traddtraf2a
Anti-Apoptotic
arbirc2bnip3lb (BNIP3L)fasmyd88nfkb1ngfa (NGF)ngfbripk1l (RIPK1)ripk2tnfatnfbtnfrsf1atnfrsf1btraf2a
TNF-Induced Apoptosis
cylda (CYLD)spata2sycp2
Other Apoptosis Genes
edar
Oxidative Stress
aifm1cybacybbglud1a (GLUD1)glud1b (GLUD1)nox1
Mitochondrial Genes
aifm1baxa (BAX)baxb (BAX)bida (BID)bnip3lb (BNIP3L)cybacybbglud1a (GLUD1)glud1b (GLUD1)glula (GLUL)ppidripk1l (RIPK1)slc25a4