RIPOR1 Gene Summary [Human]
Enables 14-3-3 protein binding activity. Involved in several processes, including establishment of Golgi localization; negative regulation of Rho guanyl-nucleotide exchange factor activity; and negative regulation of Rho protein signal transduction. Located in Golgi apparatus; cell leading edge; and membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RIPOR1 |
| Official Name | RHO family interacting cell polarization regulator 1 [Source:HGNC Symbol;Acc:HGNC:25836] |
| Ensembl ID | ENSG00000039523 |
| Bio databases IDs | |
| Aliases | RHO family interacting cell polarization regulator 1 |
| Synonyms | 2310066E14Rik, FAM65A, RGD1307772, RHO family interacting cell polarization regulator 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RIPOR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- HEAT repeats
- Filopodia upregulated, FAM65
- HR1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- cytosol
- vesicle membrane
- cell membrane leading edge
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RIPOR1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of intracellular protein transport
- protein localization in Golgi apparatus
- establishment of Golgi localization
- response to wounding
- cellular response to starvation
- Rho protein signal transduction
- positive regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- vesicle membrane
- membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- 14-3-3 protein binding