Ripor1 Gene Summary [Mouse]
Predicted to enable 14-3-3 protein binding activity. Predicted to be involved in several processes, including establishment of Golgi localization; negative regulation of Rho guanyl-nucleotide exchange factor activity; and negative regulation of Rho protein signal transduction. Located in cytoplasm. Is expressed in several structures, including adrenal gland; genitourinary system; hemolymphoid system; liver; and lung. Orthologous to human RIPOR1 (RHO family interacting cell polarization regulator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ripor1 |
| Official Name | RHO family interacting cell polarization regulator 1 [Source:MGI Symbol;Acc:MGI:1922937] |
| Ensembl ID | ENSMUSG00000038604 |
| Bio databases IDs | |
| Aliases | RHO family interacting cell polarization regulator 1 |
| Synonyms | 2310066E14Rik, FAM65A, RGD1307772, RHO family interacting cell polarization regulator 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ripor1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- HEAT repeats
- Filopodia upregulated, FAM65
- HR1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- cytosol
- vesicle membrane
- cell membrane leading edge
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ripor1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of intracellular protein transport
- protein localization in Golgi apparatus
- establishment of Golgi localization
- response to wounding
- cellular response to starvation
- Rho protein signal transduction
- positive regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- vesicle membrane
- membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- 14-3-3 protein binding