LOC100911130 Gene Summary [Rat]
This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Details
| Type | Protein Coding |
| Official Symbol | LOC100911130 |
| Official Name | mitochondrial import inner membrane translocase subunit Tim17-B-like [Source:RGD Symbol;Acc:6494590] |
| Ensembl ID | ENSRNOG00000048613 |
| Bio databases IDs | |
| Aliases | mitochondrial import inner membrane translocase subunit Tim17-B-like |
| Synonyms | DXS9822, JM3, LOC100911130, mTim17b, RGD1561744, Sfc3, TIM17B, translocase of inner mitochondrial membrane 17B |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc100911130 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TIM22
- protein binding
- Tim17/Tim22/Tim23/Pmp24 family
- transporter
Pathways
Biological processes and signaling networks where the Loc100911130 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Loc100911130 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting to mitochondrion
- protein import into mitochondrial matrix
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial inner membrane presequence translocase complex
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein transmembrane transporter activity