Timm17b Gene Summary [Mouse]

Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial inner membrane. Orthologous to human TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Timm17b
Official Name
translocase of inner mitochondrial membrane 17b [Source:MGI Symbol;Acc:MGI:1343176]
Ensembl ID
ENSMUSG00000031158
Bio databases IDs NCBI: 21855 Ensembl: ENSMUSG00000031158
Aliases translocase of inner mitochondrial membrane 17b
Synonyms DXS9822, JM3, LOC100911130, mTim17b, RGD1561744, Sfc3, TIM17B, translocase of inner mitochondrial membrane 17B
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Timm17b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TIM22
  • protein binding
  • Tim17/Tim22/Tim23/Pmp24 family
  • transporter

Pathways

Biological processes and signaling networks where the Timm17b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • infection by HIV-1
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Timm17b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein targeting to mitochondrion
  • protein import into mitochondrial matrix
  • intracellular protein transport

Cellular Component

Where in the cell the gene product is active
  • mitochondrial inner membrane presequence translocase complex
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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