Reg2 Gene Summary [Mouse]
Predicted to enable several functions, including molecular function inhibitor activity; oligosaccharide binding activity; and peptidoglycan binding activity. Acts upstream of or within myelination and suckling behavior. Located in collagen-containing extracellular matrix. Is expressed in several structures, including gut; male reproductive gland or organ; and mesenteric adipose tissue. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Reg2 |
| Official Name | regenerating islet-derived 2 [Source:MGI Symbol;Acc:MGI:97896] |
| Ensembl ID | ENSMUSG00000023140 |
| Bio databases IDs | |
| Aliases | regenerating islet-derived 2 |
| Synonyms | PSP, PTP, regenerating islet-derived 2 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Reg2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown