Reg3a Gene Summary [Mouse]
Predicted to enable several functions, including hormone activity; identical protein binding activity; and peptidoglycan binding activity. Involved in negative regulation of keratinocyte differentiation; positive regulation of keratinocyte proliferation; and positive regulation of wound healing. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut and pancreas. Orthologous to human REG3A (regenerating family member 3 alpha). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Reg3a |
| Official Name | regenerating islet-derived 3 alpha [Source:MGI Symbol;Acc:MGI:109408] |
| Ensembl ID | ENSMUSG00000079516 |
| Bio databases IDs | |
| Aliases | regenerating islet-derived 3 alpha |
| Synonyms | AV063448, Pap2, Pap II, regenerating islet-derived 3 alpha, regenerating islet-derived 3 α |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Reg3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- hormone
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space