Target List
Hotspot Coverage
AKT1, EGFR (ERBB1), ERBB3, ESR1 (ERα), FBXW7, KRAS, PIK3CA (p110-alpha), SF3B1
Whole Coding Coverage
BRCA1, BRCA2, ERBB2 (HER-2, NEU), TP53 (p53)
Carcinomas
BRCA1, BRCA2, EGFR (ERBB1), ERBB2 (HER-2, NEU), ESR1 (ERα), FBXW7, KRAS, PIK3CA (p110-alpha), SF3B1, TP53 (p53)
Invasive Breast Cancers
ERBB2 (HER-2, NEU), KRAS, PIK3CA (p110-alpha)
Invasive Ductal Carcinomas
EGFR (ERBB1), ERBB2 (HER-2, NEU), ESR1 (ERα), KRAS, PIK3CA (p110-alpha), SF3B1
Lobular Adenocarcinomas
ERBB2 (HER-2, NEU), ESR1 (ERα), PIK3CA (p110-alpha), SF3B1
Metastatic Breast Cancers
AKT1, BRCA1, BRCA2, EGFR (ERBB1), ERBB2 (HER-2, NEU), ERBB3, ESR1 (ERα), KRAS, PIK3CA (p110-alpha), SF3B1
Other Breast Cancer Genes
EGFR (ERBB1), ERBB2 (HER-2, NEU), ESR1 (ERα), KRAS, PIK3CA (p110-alpha), SF3B1