Target List
Interferons & Receptors
IFNA1, IFNA2, IFNA4, IFNAR1, IFNAR2, IFNB1, IFNE, IFNW1
Interferon-Responsive Genes
Innate Immunity
ADAR, BST2, CASP1 (ICE), CCL2 (MCP-1), CCL5 (RANTES), DDX58, GBP1, HLA-E, HLA-G, IFI27, IFI30, IFI6, IFIH1, IFIT1, IFIT2, IFIT3, IFITM1 (9-27), IFITM2, IFITM3, IRF1, IRF2, IRF7, IRF9, ISG15, ISG20, JAK2, MX1, MX2, MYD88, NMI, OAS1, OAS2, PML, SOCS1, STAT1, STAT2, TAP1 (ABCB2), TLR3, TLR7
Adaptive Immunity
CD80, CRP, MYD88, TAP1 (ABCB2)
Cytokines
CCL2 (MCP-1), CCL5 (RANTES), CXCL10 (INP10), IL15, TNFSF10 (TRAIL)
Apoptosis
ADAR, CASP1 (ICE), CCL2 (MCP-1), CCL5 (RANTES), EIF2AK2, IFI16, IFI27, IFI6, IFIH1, JAK2, MX1, MYD88, PML, STAT1, TIMP1, TLR3, TNFSF10 (TRAIL)
Other Type I Interferon Response Genes
Innate Immunity
CD86, CIITA, HLA-A, HLA-B, IFNA2, IFNA4, IFNAR1, IFNAR2, IFNB1, IRF3, IRF5, JAK1, NOS2 (iNOS), SH2D1A, STAT3, TICAM1 (TRIF), TLR8, TLR9, TMEM173, TRAF3, TYK2
Adaptive Immunity
IFNA2, IFNB1, IL10, TLR8, VEGFA
Cytokines
CD70, IL10, IL6, VEGFA
Apoptosis
BAG3, CAV1, CD70, CDKN1B (P27KIP1), IFNA2, IFNB1, IL10, IL6, MAL, MET, MNDA, PRKCZ, PSME2, SHB, TICAM1 (TRIF), TMEM173, TRAF3, VEGFA