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GeneGlobe ID: JHS-005Z | Cat. No.: | QIAseq RNA Fusion XP Panels

QIAseq RNA Fusion XP Sarcoma Panel

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

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Product Specification

Target List

Covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.Analyzes the expression of the targeted genes.Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build.

Alveolar Soft Part Sarcomas
ASPSCR1TFE3APCKMT2DPTEN
Angiosarcomas & Epitheliod Haemangioendotheliomas
CAMTA1CEP85LCICLEUTXROS1TFE3YAP1AKT1ALKAPCARARID1AARID2ASXL1ATMBRAFCDKN2A (P16INK4A)CICCREBBP (CBP)CTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)ERBB3EZH2FBXW7FGFR1FGFR2FGFR3FGFR4FLT3HRASJAK3KMT2DKRASMED12METMLH1MPLNCOR1NOTCH2NRASPAX5PBRM1PIK3CA (p110-alpha)PIK3CBPIK3R1 (p85-ALPHA)PLCG1PTENTERTTRAF7TRRAPZFHX3
Askins Tumors
ERGEWSR1FLI1FUS
Chondrosarcomas
ACVR2ACDX1EWSR1FN1HEY1IRF2BP2NCOA2NR4A3 (NOR1)TAF15TCF12TFGALKARARID1ACDKN2A (P16INK4A)DNMT3AERBB3H3-3AHRASIDH1IDH2IRS4JAK1KMT2DMLLT3NRASPOLEPTENSMAD2 (MADH2)SMARCB1TERTZFHX3
Clear Cell Sarcomas
ATF1CREB1EWSR1FLI1NUTM2BYWHAEBRAFCDKN2A (P16INK4A)EGFR (ERBB1)NRASPTEN
Congenital (Infantile) Fibrosarcomas
ETV6METNTRK3TFG
Dermatofibrosarcoma Protuberans
COL1A1PDGFBFGFR1MED12
Dermatofibrosarcomas Protuberans
COL1A1PDGFB
Desmoplastic Small Round Cell Tumors
ERGEWSR1FLI1PATZ1WT1APCCICCREBBP (CBP)DAXXEGFR (ERBB1)
Endometrial Stromal Sarcomas
ALKBCORCXorf67EPC1FN1JAZF1MBTD1MEAF6NUTM2ANUTM2BPHF1SUZ12YWHAEZC3H7BASXL1CTNNB1ERBB3FBXW7FGFR2FLT3KRASMED12PIK3CA (p110-alpha)
Epithelioid Sarcomas
CREB3L1CREB3L2EWSR1FUSKLF17SS18SSX1DICER1SMARCB1
Ewing's Sarcomas
CICERGETV1ETV4EWSR1FEVFLI1FOXO4FUSNFATC2SMARCA5SP3ALKAPCARARID1AARID2ASXL1ATMBCORBRAFCBLCD209CD79BCDKN2A (P16INK4A)CICCREBBP (CBP)CTNNB1DAXXDGCR8DICER1DNMT3AEGFR (ERBB1)ERBB2 (HER-2, NEU)EZH2FBXW7FGFR1FGFR3FGFR4GNASHRASIDH1IDH2IRS4KIT (CD117)KMT2DKRASMED12METMLH1MLLT3MYOD1NCOR1NCOR2NOTCH2NRASPAX5PBRM1PIK3CA (p110-alpha)PIK3CBPIK3R1 (p85-ALPHA)PLCG1POLEPTENRECQL4SMARCB1TERTTNCTRAF7TRRAPZFHX3
Fibrosarcomas
BRAFCOL1A1CREB3L1CREB3L2EWSR1FUSLMNANTRK1PDGFBTOM1L2BCORCDKN2A (P16INK4A)CTNNB1EGFR (ERBB1)EZH2FGFR3FLT3KIT (CD117)KRASNRASPOLEPTENTERTTRAF7
Leiomyosarcomas
EWSR1HMGA2PBX3WT1ALKAPCARARID1AARID2ASXL1ATMCBLCREBBP (CBP)DAXXDNMT3AERBB3EZH2FGFR1FGFR3JAK1JAK3METMPLNCOR1PAX5RECQL4TRAF7
Liposarcomas
DDIT3 (GADD153, CHOP)EWSR1FUSHMGA2LGR5NUP107AKT1ALKAPCARID1AATMBRAFCBLCD79BCDKN2A (P16INK4A)CICCTNNB1DICER1DNMT3AEGFR (ERBB1)ERBB2 (HER-2, NEU)FBXW7FGFR1FGFR2FGFR3HRASJAK1JAK3KIT (CD117)KMT2DKRASMLH1MPLNCOR1NOTCH2PBRM1PDGFRAPIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)POLEPTENRECQL4TERTZFHX3
Myofibroblastic Sarcomas
ALKLMNANTRK1RELAROS1SRFTFGTPM3YWHAE
Myxofibrosarcomas
CREB3L1CREB3L2FUS
Myxoid Chondrosarcomas
NR4A3 (NOR1)TAF15
Perivascular Epithelioid Cell Tumors (PEComa)
DVL2SFPQTFE3ALKATMCICJAK3MED12NOTCH2
Pleomorphic Sarcomas (Malignant Fibrous Histiocytoma)
CITED2MED12PRDM10ALKAPCARARID1AARID2ASXL1ATMBRAFCD79BCDKN2A (P16INK4A)CICCTNNB1DICER1DNMT3AEGFR (ERBB1)ERBB2 (HER-2, NEU)ERBB3EZH2FBXW7FGFR1FGFR4FLT3HRASIDH1JAK1JAK3KIT (CD117)KMT2DKRASMETMLH1MYOD1NCOR1NOTCH2NRASPAX5PBRM1PIK3CA (p110-alpha)POLEPTENPTPN11SMARCB1TERTTRAF7ZFHX3
Rhabdoid Tumors
NCOA4RETCREBBP (CBP)PBRM1SMARCB1
Rhabdomyosarcomas
CITED2EWSR1FLI1FOXO1NCOA1NCOA2PAX3PAX7SRFTEAD1VGLL2ALKAPCARARID1AARID2ASXL1ATMBCORBRAFCDKN2A (P16INK4A)CICCREBBP (CBP)CTNNB1DAXXDGCR8DICER1DNMT3AERBB2 (HER-2, NEU)ERBB3EZH2FBXW7FGFR1FGFR2FGFR3FGFR4FLT3GNASHRASIRS4KIT (CD117)KMT2DKRASMED12METMLH1MPLMYOD1NCOR2NOTCH2NRASPDGFRAPIK3CA (p110-alpha)POLEPTENPTPN11RECQL4SH2B3SMARCB1TNCTRAF7TRRAPWNK2ZFHX3
Small Round Cell Tumors
ERGETV1EWSR1FEVFLI1FOXO1PAX3
Solitary Fibrous Tumors
NAB2STAT6ALKAPCARID2CBLFBXW7FGFR1FGFR3KMT2DPIK3R1 (p85-ALPHA)PTENTERT
Synovial Sarcomas
COL6A3CSF1 (MCSF)S100A10SS18SS18L1SSX1SSX2SSX4BARID2BCORBRAFCTNNB1EGFR (ERBB1)FGFR1HRASKMT2DKRASMED12MLH1PDGFRAPIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PTENTERTTRAF7TRRAPZFHX3
Undifferentiated; Unclassified or Other Sarcomas
ATF1BCORCCNB3CREMERGETV4EWSR1FGF1FGFR1FLI1FN1FOXO1FUSGLI1JAZF1MAML3MKL2NPM1PAX3PLAG1POU5F1 (OCT4)RUNX1 (AML1)RUNX1T1SUZ12USP6ARID2ATMCICCREBBP (CBP)CTNNB1DICER1EGFR (ERBB1)FBXW7FLT3H3-3AMED12METNCOR1NOTCH2PBRM1SH2B3
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFR (ERBB1)EML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
General Sarcoma Markers
CD248CD34EGFR (ERBB1)ERGMCAMPDGFRAPDGFRBPROM1S100A1SOX2TERTVIM
Sarcoma Type & Subtype Markers
Alveolar Soft Part Sarcomas​
INHBATFE3
Angiosarcomas & Epitheliod Haemangioendotheliomas​
CAMTA1DESERGFOSBMYCPECAM1TFE3
Chondrosarcomas​
AMACRFLI1SATB2VEGFA
Dermatofibrosarcoma Protuberans​
GRIA2
Desmoplastic Small Round Cell Tumors​
WT1
Endometrial Stromal Sarcomas​
ACTA2 (α-SMA)BCORDESEGFR (ERBB1)KIT (CD117)
Epitheliod Sarcomas​
CD109
Ewing's Sarcomas​
ALDH1A1 (RALDH1)ATP1A1BCL11BCCND1CD99FLI1GLG1NKX2-2PAX7RRM2SLFN11STEAP1VEGFA
Fibromyxoid Sarcomas​
ANO1MUC4
Follicular Dendritic Cell Sarcomas​
CLUCR2FCER2
Gastrointestinal Stromal Tumors (GIST)​
ACTA2 (α-SMA)ANO1CALCRLCD44COL22A1IGF1IGF1RIGF2KIT (CD117)MUC4PROM1SDHASDHB
Gonadal Stromal Tumors​
CD99INHBAWT1
Intimal Sarcomas​
CDK4MDM2PDGFRA
Leiomyosarcomas​
ACTA2 (α-SMA)ANO1DES
Liposarcomas​
CDK4DESMDM2
Malignant Peripheral Nerve Sheath Tumors (MPNST)​
ALKBCL2CDK4GFAPSMARCB1SOX10TLE1
Myofibroblastic Sarcomas​
ALKBCL2RB1
Myxofibrosarcomas​
AMACRASS1CDK4ITGA10MDM2MET
Osteosarcomas​
ALDH1A1 (RALDH1)CDK4FLI1LAMP3MDM2SATB2VEGFA
Rhabdoid Tumors​
ETV4SMARCB1
Rhabdomyosarcomas​
ACTA2 (α-SMA)ALDH1A1 (RALDH1)ALKCDK4DESIGFBP2MDM2MYOD1MYOGPAX7
Solitary Fibrous Tumors​
ALDH1A1 (RALDH1)GRIA2STAT6
Spindle Cell Sarcomas​
AFAP1L1
Synovial Sarcomas​
ANO1BCL2CDCA2EZH2FLI1INHBAKIF14MUC4PAX7TLE1
Undifferentiated; Unclassified or Other Sarcomas​
CCNB3SOX10WT1
Possible Prognostic Significance
Associated with Invasiveness​
CD44PROM1STEAP1TERT
Associated with Metastasis​
ACKR3CD9CDCA2CTAG1BCXCR4EZH2IGFBP7ITGA10KIF14
Chemotherapy Resistance​
ALDH1A1 (RALDH1)AMACRCEBPBPDGFRAPDGFRBSTEAP1
Clinical Outcome or Tumor Grade Indicators​
AFAP1L1AMACRCD109CD274 (PD-L1)CD274 (PD-L1)CD44CD9CDCA2CDK4CTAG1BCXCR4EZH2GPS2IGF1RIGFBP2KIF14MCAMMDM2STEAP1TERTVEGFA
Hypoxia & Oxidative Stress​
HIF1ASTEAP1VEGFA
Immunotherapy Response​
CD274 (PD-L1)CD274 (PD-L1)CTAG1B
Treatment Targets or Treatment Indicators​
IGF1RRRM2SLFN11
Cancer Stem Cell & Proliferation Markers
ALDH1A1 (RALDH1)CD44MKI67PDGFRAPDGFRB
Expression Affected by Genomic Variation
ALKATP1A1BCL11BBCORERGETV4FLI1GLG1NKX2-2SOX2WT1
Chordomas
ALKAPCARARID1AATMCBLCDKN2A (P16INK4A)CTNNB1KIT (CD117)KMT2DNRASPIK3CA (p110-alpha)PTENSMARCB1
Gastrointestinal Stromal Tumors (GIST)
ALKAPCARARID1AARID2ASXL1BRAFCBLCDKN2A (P16INK4A)CREBBP (CBP)DAXXDICER1EGFR (ERBB1)FBXW7FGFR1H3-3AJAK1KIT (CD117)KMT2DKRASMED12MYOD1NOTCH2PBRM1PDGFRAPIK3CA (p110-alpha)POLEPTENRECQL4SH2B3TERTTRAF7ZFHX3
Kaposi Sarcomas
BRAFPIK3CA (p110-alpha)
Malignant Peripheral Nerve Sheath Tumors (MPNST)
ARID2BCORBRAFCBLCDKN2A (P16INK4A)KRASNRASPAX5PDGFRATERT
Osteosarcomas
AKT1ALKAPCARARID1AASXL1BCORBRAFCBLCD209CDKN2A (P16INK4A)CREBBP (CBP)DAXXDNMT3AEGFR (ERBB1)FBXW7FGFR3FGFR4FLT3GNASH3-3AIDH2JAK1JAK3KMT2DMED12METMLH1MLLT3NCOR1NCOR2NOTCH2PBRM1PIK3CA (p110-alpha)PIK3CBPIK3R1 (p85-ALPHA)POLEPTENRECQL4SMAD2 (MADH2)TERTTNCTRRAPWNK2ZFHX3

Product Resources

icon_0041_download-s Download Target List
icon_0041_download-s Detailed Target List for each Analyte
File Size: 25.54 KBLanguage: English

Resources

Safety Data Sheets (1)
Safety Data Sheets
Kit Handbooks (1)
QIAseq RNA Fusion XP Panel Handbook
PDF (3MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis
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