Target List
Exons
ASXL1, ATRX, CALR, CBL, CBLB, CBLC, CSF3R, EZH2, FBXW7, GATA1, GNAS, HRAS, IDH1, IDH2, JAK3, KIT, KMT2A, MYD88, NOTCH1, NPM1, PDGFRA, PTEN, SF3B1, SMC1A, SMC3, SRSF2, STAT3, U2AF1, WT1
Exons & Hotspots
BRAF, EGFR, FLT3, JAK2, KRAS, MPL, NRAS, PTPN11
Hotspots
ALK, ARAF, ARID1A, ATM, B2M, BCL2, BCL6, BTK, CARD11, CD79B, CDKN2A, CEBPA, CHEK2, CREBBP, CSF1R, CTNNB1, CXCR4, DDX41, DNMT3A, FGFR3, GNA13, GNB1, JAK1, KMT2D, MAP2K1, MTOR, MYC, PIK3CA, PIM1, PLCG2, RET, RHOA, RRAS, RUNX1, SETBP1, SOCS1, STAT5B, TNFAIP3, UBA1, XPO1
Whole Coding
GATA2, TET2, TP53
Leukemia
ABL1, ALK, ARAF, ASXL1, ATRX, BCL2, BRAF, BTK, CBL, CBLB, CBLC, CDKN2A, CEBPA, CREBBP, CSF1R, DDX41, DNMT3A, EZH2, FBXW7, FLT3, GATA1, GATA2, GNAS, GNB1, HRAS, IDH1, IDH2, JAK1, JAK2, JAK3, KIT, KMT2A, KRAS, MAP2K1, MPL, MTOR, MYC, MYD88, NOTCH1, NPM1, NRAS, PDGFRA, PLCG2, PTEN, PTPN11, RRAS, RUNX1, SETBP1, SF3B1, SMC1A, SRSF2, TET2, TP53, U2AF1, UBA1, WT1, XPO1
Lymphomas
ALK, ARAF, ARID1A, ATM, ATRX, B2M, BCL2, BCL6, BRAF, BTK, CARD11, CBLB, CD79B, CDKN2A, CHEK2, CREBBP, CSF1R, CTNNB1, DNMT3A, EZH2, GNA13, GNAS, IDH1, IDH2, JAK1, JAK3, KMT2D, MAP2K1, MTOR, MYC, MYD88, NOTCH1, NRAS, PIK3CA, PIM1, PLCG2, RHOA, SF3B1, SOCS1, STAT3, STAT5B, TET2, TNFAIP3, TP53, UBA1, XPO1
Myelodysplastic Syndromes & Myeloproliferative Neoplasms
ASXL1, ATRX, CALR, CBL, CEBPA, CSF1R, CSF3R, DDX41, DNMT3A, EZH2, FLT3, GATA2, GNAS, GNB1, IDH1, IDH2, JAK2, JAK3, KIT, KRAS, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PTPN11, RUNX1, SETBP1, SF3B1, SMC3, SRSF2, STAT3, STAT5B, TET2, TP53, U2AF1, WT1
Other Myeloid Neoplasms
ALK, CSF1R, CXCR4, EGFR, FGFR3, RET, RRAS, U2AF1, UBA1