Caprin2 Gene Summary [Rat]
Predicted to enable signaling receptor binding activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; positive regulation of dendritic spine morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including centrosome; mitochondrion; and nucleoplasm. Predicted to be part of receptor complex. Predicted to be active in cytoplasm. Orthologous to human CAPRIN2 (caprin family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Caprin2 |
| Official Name | caprin family member 2 [Source:RGD Symbol;Acc:1593683] |
| Ensembl ID | ENSRNOG00000047319 |
| Bio databases IDs | |
| Aliases | caprin family member 2 |
| Synonyms | Adir, AV149826, C1QDC1, C1q Domain Containing 1, caprin family member 2, EEG-1, RNG140 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Caprin2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Caprin-1 dimerization domain
- Protein of unknown function, DUF612
- Cytoplasmic activation/proliferation-associated protein-1 C term
- protein binding
- receptor binding
- C1q domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cataract
- colorectal cancer
regulates
- DNA endogenous promoter
- DNA promoter
- RNA polymerase II
role in cell
- apoptosis
- growth
- translation in
- morphogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- centrosome
- Mitochondria
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Caprin2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of dendritic spine morphogenesis
- negative regulation of cell growth
- positive regulation of canonical Wnt receptor signaling pathway
- cell differentiation
- dorsal/ventral axis specification
- positive regulation of transcription from RNA polymerase II promoter
- negative regulation of translation
- positive regulation of dendrite morphogenesis
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- mitochondrion
- cytosol
- receptor complex
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- metal ion binding
- receptor binding