GeneGlobe ID: LXHS-3200Z | Cat. No.: Varies | QIAseq xHyb Long Read Panels

QIAseq xHYB Long Read Hereditary Cancer Panel

Product Specification

Target List

The QIAseq xHYB Long Read Hereditary Cancer Panel enables comprehensive detection of hereditary cancer risk by targeting 95 full-length genes with known large structural variants linked to cancer progression. By capturing entire gene regions—including exons, introns, and UTRs—this panel allows for complete, unbiased characterization of complex variants often missed by short-read methods. Designed for high-resolution structural variant analysis, it supports confident identification of cancer-driving mutations in inherited cancer predisposition genes, providing a powerful tool for cancer research.

Hereditary Breast Cancer
ACTRT1APC2APOBEC3BATMATRBARD1BCL3BLMBRCA1BRCA2BRIP1CDH1CDKN2ACHEK2COL7A1DOCK8FANCAFANCCFANCMGSTT1IGFBP5KANSL1MRE11MSH6MUTYHNBNOR4C11PALB2PMS2POLD1PTENRAD51CRAD51DRNF5SLX4STK11TMTC3TP53WRN
Hereditary Breast and Ovarian Cancer Syndrome (HBOC)
ATMBARD1BRCA1BRCA2CHEK2CNTNAP2FIBINHRASLINC00583MSH2NF1PALB2PMS1PMS2PPM1DRAD51CRAD51DSMARCA4TP53ULK2
Hereditary Colorectal Cancer
AK3ANKRD24APCATMBCRBRCA2CDH18EPCAMFOCADGREM1LTBP3MFHAS1MIR491MIR646MLH1MSH2MSH6MUTYHNELL1NKX2-3ORM1PMS2PTPRJRAD54LRERGLSEMA3DSLIT2SMAD4TEKTSC2TTF2
Hereditary Lung Cancer
BAP1CHEK2EGFRTP53
Hereditary Ovarian Cancer
ATMATRBARD1BRCA1BRCA2BRIP1CDH1CHEK2DCCFANCMMLH1MSH2MSH6NBNPALB2PMS2RAD50RAD51CRAD51DSTK11TP53
Hereditary Pancreatic Cancer
ARATMBRCA1BRCA2CDKN2ACNTN1CPA1DYNLRB2GPC6LAMA1MSH2PALB2PCSK1PLXDC2POLERSPO2SSC5DSTK11TYRO3ZFHX3
Hereditary Prostate Cancer
ATMATRBRCA2CDKN2ACHEK2MSH2PABPC1PALB2SLC25A13TSC2

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Resources

Kit Handbooks (1)
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Certificates of Analysis (1)
QIAseq xHYB Long Read Panels offer highly specific and sensitive hybrid capture-based target enrichment for long-read sequencing, ensuring complete and uniform coverage across complex genomic regions, including high-GC content and structural variations. These panels are optimized for PacBio and ONT long-read systems and provide high-quality data for accurate and reliable downstream analyses. Their flexibility and customization options allow researchers to tailor experiments to their specific needs and budgets, while an optimized, user-friendly workflow ensures ease of use.