Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Hotspot Coverage
AKT1EGFR (ERBB1)ERBB3ESR1 (ERα)FBXW7KRASPIK3CA (p110-alpha)SF3B1
Whole Coding Coverage
BRCA1BRCA2ERBB2 (HER-2, NEU)TP53 (p53)
Carcinomas
BRCA1BRCA2EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)FBXW7KRASPIK3CA (p110-alpha)SF3B1TP53 (p53)
Invasive Breast Cancers
ERBB2 (HER-2, NEU)KRASPIK3CA (p110-alpha)
Invasive Ductal Carcinomas
EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)KRASPIK3CA (p110-alpha)SF3B1
Lobular Adenocarcinomas
ERBB2 (HER-2, NEU)ESR1 (ERα)PIK3CA (p110-alpha)SF3B1
Metastatic Breast Cancers
AKT1BRCA1BRCA2EGFR (ERBB1)ERBB2 (HER-2, NEU)ERBB3ESR1 (ERα)KRASPIK3CA (p110-alpha)SF3B1
Other Breast Cancer Genes
EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)KRASPIK3CA (p110-alpha)SF3B1