ZNF160 Gene Summary [Human]
The protein encoded by this gene is a Kruppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2016]
Details
| Type | Protein Coding |
| Official Symbol | ZNF160 |
| Official Name | zinc finger protein 160 [Source:HGNC Symbol;Acc:HGNC:12948] |
| Ensembl ID | ENSG00000170949 |
| Bio databases IDs | |
| Aliases | zinc finger protein 160 |
| Synonyms | F11, HKr18, HZF5, KR18, zinc finger protein 160 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF160 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- krueppel associated box
- transcription regulator
- Zinc-finger double domain
- KRAB (Kruppel-associated box) domain -A box
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF160 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- hemopoiesis
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity