IGKV1D-12 Gene Summary [Human]
Predicted to be involved in immune response. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Immunoglobulin Variable Gene |
| Official Symbol | IGKV1D-12 |
| Official Name | immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746] |
| Ensembl ID | ENSG00000278857 |
| Bio databases IDs | |
| Aliases | immunoglobulin kappa variable 1D-12 |
| Synonyms | immunoglobulin kappa variable 1D-12, immunoglobulin κ variable 1D-12, L19 |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the IGKV1D-12 gene in human plays a role, providing insight into its function and relevance in health or disease.
- Altered T Cell and B Cell Signaling in Rheumatoid Arthritis
- B Cell Development
- B Cell Receptor Signaling
- Communication between Innate and Adaptive Immune Cells
- FcγRIIB Signaling in B Lymphocytes
- IL-15 Signaling
- p70S6K Signaling
- PI3K Signaling in B Lymphocytes
- Role of NFAT in Regulation of the Immune Response
- Systemic Lupus Erythematosus Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IGKV1D-12 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- adaptive immune response
- immunoglobulin production
Cellular Component
Where in the cell the gene product is active
- immunoglobulin complex
- extracellular space
- extracellular vesicular exosome
- blood microparticle
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- antigen binding