Pdpr Gene Summary [Mouse]
Located in mitochondrion. Is expressed in cerebral cortex; heart; and liver. Orthologous to human PDPR (pyruvate dehydrogenase phosphatase regulatory subunit). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pdpr |
| Official Name | pyruvate dehydrogenase phosphatase regulatory subunit [Source:MGI Symbol;Acc:MGI:2442188] |
| Ensembl ID | ENSMUSG00000033624 |
| Bio databases IDs | |
| Aliases | pyruvate dehydrogenase phosphatase regulatory subunit |
| Synonyms | 4930402E16RIK, mKIAA1990, Pdp1r, PDP3, pyruvate dehydrogenase phosphatase regulatory subunit, RGD1308307 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pdpr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FAD dependent oxidoreductase central domain
- Glycine cleavage T-protein C-terminal barrel domain
- Aminomethyltransferase folate-binding domain
- glycine cleavage system aminomethyltransferase GcvT
- FAD dependent oxidoreductase
- sarcosine oxidase, monomeric form
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pdpr gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrial matrix
- mitochondrion
- pyruvate dehydrogenase (lipoamide) phosphatase complex