Pdpr Gene Summary [Rat]

Predicted to be active in mitochondrial matrix. Orthologous to human PDPR (pyruvate dehydrogenase phosphatase regulatory subunit). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pdpr
Official Name
pyruvate dehydrogenase phosphatase regulatory subunit [Source:RGD Symbol;Acc:1308307]
Ensembl ID
ENSRNOG00000022593
Bio databases IDs NCBI: 307852 Ensembl: ENSRNOG00000022593
Aliases pyruvate dehydrogenase phosphatase regulatory subunit
Synonyms 4930402E16RIK, mKIAA1990, Pdp1r, PDP3, pyruvate dehydrogenase phosphatase regulatory subunit, RGD1308307
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pdpr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FAD dependent oxidoreductase central domain
  • Glycine cleavage T-protein C-terminal barrel domain
  • Aminomethyltransferase folate-binding domain
  • glycine cleavage system aminomethyltransferase GcvT
  • FAD dependent oxidoreductase
  • sarcosine oxidase, monomeric form

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • Alzheimer disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pdpr gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • mitochondrial matrix
  • mitochondrion
  • pyruvate dehydrogenase (lipoamide) phosphatase complex

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.