Cd207 Gene Summary [Mouse]
Enables carbohydrate binding activity. Predicted to be involved in defense response to virus and immune response. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in epidermis; lymph node; spleen; and thymus. Orthologous to human CD207 (CD207 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd207 |
| Official Name | CD207 antigen [Source:MGI Symbol;Acc:MGI:2180021] |
| Ensembl ID | ENSMUSG00000034783 |
| Bio databases IDs | |
| Aliases | CD207 antigen |
| Synonyms | CD207 antigen, CD207 molecule, CLEC4K, LANGERIN, LOC686223, RGD1565913 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd207 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- prefoldin
- Lectin C-type domain
- protein binding
- carbohydrate binding
- mannose binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Langerhans cell histiocytosis
- Birbeck granule deficiency
- Erdheim-Chester disease
- EGFR mutation positive adenocarcinoma of the lung
- EGFR mutation positive non-small cell lung cancer
- lung adenocarcinoma formation
- EGFR expression positive non-squamous non-small cell lung cancer
- skin neoplasia
- skin basal cell carcinoma
- basal cell skin cancer
regulates
- IgG3
- IgM
- IgG2a
- IgA
- IgG1
role in cell
- quantity
- formation
- migration
- abnormal morphology
- depletion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- endocytic vesicle membrane
- cell surface
- intracellular space
- pericentriolar regions
- cellular membrane
- endosomal membrane
- Birbeck granules
- recycling endosomes
- early endosomes
- endocytotic vesicle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd207 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- interspecies interaction between organisms
- defense response to virus
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- endocytic vesicle
- clathrin-coated endocytic vesicle membrane
- external side of plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- mannose binding
- protein binding
- carbohydrate binding