Uba52 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in optic vesicle. Orthologous to human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uba52 |
| Official Name | ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:MGI Symbol;Acc:MGI:98887] |
| Ensembl ID | ENSMUSG00000090137 |
| Bio databases IDs | |
| Aliases | ubiquitin A-52 residue ribosomal protein fusion product 1 |
| Synonyms | CEP52, D8Ertd21e, Gm1863, HUBCEP52, L40, RPL40, Rps27a, Ubb, Ubc, UBIQUITIN A, ubiquitin A-52 residue ribosomal protein fusion product 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uba52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquitin family
- Ribosomal L40e family
- structural constituent of ribosome
- Ubl1_cv_Nsp3_N-like
- Ubiquitin homologues
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Uba52 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endocytic vesicle membrane
- intracellular space
- cellular membrane
- ribosome
- Nucleus
- Plasma Membrane
- Endoplasmic Reticulum
- cytosol
- endoplasmic reticulum membrane
- mitochondrial outer membrane
- endosomal membrane
- nucleoplasm
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Uba52 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein modification process
- cytoplasmic translation
- modification-dependent protein catabolic process
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- cytosolic small ribosomal subunit
- endoplasmic reticulum
- synapse
- cytosolic large ribosomal subunit
- mitochondrial outer membrane
- lysosomal membrane
- plasma membrane
- nucleoplasm
- endoplasmic reticulum membrane
- nucleus
- extracellular space
- extracellular vesicular exosome
- cytoplasm
- vesicle
- cytosol
- endosome membrane
- endocytic vesicle membrane
Molecular Function
What the gene product does at the molecular level
- ubiquitin protein ligase binding
- protein binding
- structural constituent of ribosome
- protein tag