Pcdha11 Gene Summary [Mouse]

Predicted to be involved in cell adhesion. Located in membrane. Is expressed in brain. Orthologous to human PCDHA11 (protocadherin alpha 11). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Retained Intron
Official Symbol
Pcdha11
Official Name
protocadherin alpha 11 [Source:MGI Symbol;Acc:MGI:1298372]
Ensembl ID
ENSMUSG00000102206
Bio databases IDs NCBI: 12942 Ensembl: ENSMUSG00000102206
Aliases protocadherin alpha 11
Synonyms A830022B16Rik, CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11, protocadherin alpha 11, protocadherin α 11
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdha11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin-like
  • Cadherin repeat-like domain
  • Cadherin C-terminal cytoplasmic tail, catenin-binding region

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cellular membrane
  • Plasma Membrane
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdha11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nervous system development
  • cell adhesion
  • homophilic cell adhesion

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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