Itfg1 Gene Summary [Mouse]

Predicted to be located in extracellular region and membrane. Predicted to be active in plasma membrane. Is expressed in extraembryonic component; nervous system; and neural retina. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Itfg1
Official Name
integrin alpha FG-GAP repeat containing 1 [Source:MGI Symbol;Acc:MGI:106419]
Ensembl ID
ENSMUSG00000031703
Bio databases IDs NCBI: 71927 Ensembl: ENSMUSG00000031703
Aliases integrin alpha FG-GAP repeat containing 1
Synonyms 2310047C21Rik, CDA08, D8Wsu49e, integrin alpha FG-GAP repeat containing 1, integrin α FG-GAP repeat containing 1, LINKIN, LNKN-1, LOC103694297, T-cell immunomodulatory, TIP
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Itfg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FG-GAP-like repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • rheumatoid arthritis
regulated by
  • megakaryocytes

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Extracellular Space
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Itfg1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.