MCF2L2 Gene Summary [Human]

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MCF2L2
Official Name
MCF.2 cell line derived transforming sequence-like 2 [Source:HGNC Symbol;Acc:HGNC:30319]
Ensembl ID
ENSG00000053524
Bio databases IDs NCBI: 23101 Ensembl: ENSG00000053524
Aliases MCF.2 cell line derived transforming sequence-like 2
Synonyms ARHGEF22, KIAA0861, MCF.2 cell line derived transforming sequence-like 2
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MCF2L2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain in homologues of a S
  • SPEC
  • Spectrin repeats
  • RhoGEF
  • Divergent CRAL/TRIO domain
  • PH domain
  • Pleckstrin homology-like domain
  • RhoGEF domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic scoliosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MCF2L2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • guanyl-nucleotide exchange factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.