NOL4 Gene Summary [Human]

Predicted to enable RNA binding activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
NOL4
Official Name
nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870]
Ensembl ID
ENSG00000101746
Bio databases IDs NCBI: 8715 Ensembl: ENSG00000101746
Aliases nucleolar protein 4, cancer/testis antigen 125
Synonyms 1700013J13RIK, 4930568N03Rik, CT125, Gm1262, HRIHFB2255, NOLP, nucleolar protein 4
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NOL4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Integrase zinc binding domain
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • small cell lung cancer
  • non-insulin-dependent diabetes mellitus
  • neuroticism
  • metabolic syndrome X
  • schizophrenia
  • tinnitus
regulated by
  • mir-30 (includes others)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human NOL4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.