Nol4 Gene Summary [Mouse]

Predicted to be located in nucleolus. Is expressed in central nervous system and sensory organ. Orthologous to human NOL4 (nucleolar protein 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nol4
Official Name
nucleolar protein 4 [Source:MGI Symbol;Acc:MGI:2441684]
Ensembl ID
ENSMUSG00000041923
Bio databases IDs NCBI: 319211 Ensembl: ENSMUSG00000041923
Aliases nucleolar protein 4
Synonyms 1700013J13RIK, 4930568N03Rik, CT125, Gm1262, HRIHFB2255, NOLP, nucleolar protein 4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nol4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Integrase zinc binding domain
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • small cell lung cancer
  • non-insulin-dependent diabetes mellitus
  • neuroticism
  • metabolic syndrome X
  • schizophrenia
  • tinnitus
regulated by
  • mir-30 (includes others)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nol4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.