RHBG Gene Summary [Human]
This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Details
| Type | Protein Coding |
| Official Symbol | RHBG |
| Official Name | Rh family B glycoprotein [Source:HGNC Symbol;Acc:HGNC:14572] |
| Ensembl ID | ENSG00000132677 |
| Bio databases IDs | |
| Aliases | Rh family B glycoprotein |
| Synonyms | Rhesus blood group-associated B glycoprotein, Rh family B glycoprotein, SLC42A2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RHBG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ankyrin binding
- protein binding
- ammonium transporter
- transporter
- Ammonium Transporter Family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytoskeleton
- cellular membrane
- basolateral membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RHBG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ammonium transmembrane transport
- carbon dioxide transmembrane transport
- ammonia homeostasis
- transepithelial ammonium transport
Cellular Component
Where in the cell the gene product is active
- basolateral plasma membrane
- plasma membrane
- spectrin-associated cytoskeleton
Molecular Function
What the gene product does at the molecular level
- ammonium transmembrane transporter activity
- ankyrin binding
- carbon dioxide transmembrane transporter activity