TRMO Gene Summary [Human]

Enables tRNA (adenine-N6-)-methyltransferase activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TRMO
Official Name
tRNA methyltransferase O [Source:HGNC Symbol;Acc:HGNC:30967]
Ensembl ID
ENSG00000136932
Bio databases IDs NCBI: 51531 Ensembl: ENSG00000136932
Aliases tRNA methyltransferase O
Synonyms 5830415F09Rik, C9orf156, HSPC219, NAP1, RGD1305420, tRNA methyltransferase O
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRMO often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tRNA (adenine)-methyltransferase
  • TrmO C-terminal domain
  • enzyme
  • protein binding
  • Escherichia coli YaeB and related proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • papillary thyroid carcinoma
  • thyroid carcinoma
  • epithelial thyroid cancer
  • papillary thyroid cancer
  • differentiated thyroid carcinoma
regulated by
  • cisplatin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TRMO gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • tRNA methylation

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.