DMAC1 Gene Summary [Human]
Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrial inner membrane. Colocalizes with mitochondrial respiratory chain complex I. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | DMAC1 |
| Official Name | distal membrane arm assembly complex 1 [Source:HGNC Symbol;Acc:HGNC:30536] |
| Ensembl ID | ENSG00000137038 |
| Bio databases IDs | |
| Aliases | distal membrane arm assembly complex 1, distal membrane arm assembly component 1 |
| Synonyms | 1700027K24Rik, 3110001D03Rik, C9orf123, distal membrane arm assembly complex 1, distal membrane arm assembly component 1, RGD1309148, TMEM261 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DMAC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4536)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DMAC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex I assembly
Cellular Component
Where in the cell the gene product is active
- respiratory chain complex I
- mitochondrial inner membrane