WDR20 Gene Summary [Human]
This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Details
| Type | Processed Transcript |
| Official Symbol | WDR20 |
| Official Name | WD repeat domain 20 [Source:HGNC Symbol;Acc:HGNC:19667] |
| Ensembl ID | ENSG00000140153 |
| Bio databases IDs | |
| Aliases | WD repeat domain 20 |
| Synonyms | 2310040A13Rik, 4930421J07Rik, Bun107, DMR, Wdr20a, WD repeat domain 20 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WDR20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- protein binding
- protease activator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human WDR20 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- ubiquitin-specific protease activator activity