OXER1 Gene Summary [Human]
Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | OXER1 |
| Official Name | oxoeicosanoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:24884] |
| Ensembl ID | ENSG00000162881 |
| Bio databases IDs | |
| Aliases | oxoeicosanoid receptor 1, 5-oxo-ETE acid G-protein-coupled receptor 1, OXE receptor |
| Synonyms | GPCR, GPR170, oxoeicosanoid receptor 1, R527, TG1019 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OXER1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding
- 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
- 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OXER1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
- G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
- 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
- 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding