FCAMR Gene Summary [Human]

Predicted to enable IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
FCAMR
Official Name
Fc fragment of IgA and IgM receptor [Source:HGNC Symbol;Acc:HGNC:24692]
Ensembl ID
ENSG00000162897
Bio databases IDs NCBI: 83953 Ensembl: ENSG00000162897
Aliases Fc fragment of IgA and IgM receptor, Fc alpha and mu receptor, Fc alpha/mu Receptor
Synonyms CD351, Fc alpha and mu receptor, FCALPHA / FCMU receptor, Fcalpha/muR, FCA/MR, Fc receptor, IgA, IgM, high affinity, Fc α and mu receptor, Fc α/mu r, FKSG87, LOC681814
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FCAMR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Immunoglobulin V-Type
  • immunoglobulin domain
  • Immunoglobulin like
  • IgA binding
  • immunoglobulin binding
  • transmembrane receptor
  • Immunoglobulin V-set domain

Pathways

Biological processes and signaling networks where the FCAMR gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • angioimmunoblastic T-cell lymphoma
  • T-cell non-Hodgkin disease
  • mature T-cell neoplasia
  • thrombocytopenia
regulated by
regulates
  • IgM
role in cell
  • differentiation
  • function
  • antigen presentation by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human FCAMR gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • adaptive immune response

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • transmembrane signaling receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.