Fcamr Gene Summary [Mouse]
Enables IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within immune response. Predicted to be active in plasma membrane. Is expressed in brain; cerebellum; and spinal cord. Orthologous to human FCAMR (Fc alpha and mu receptor). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fcamr |
| Official Name | Fc receptor, IgA, IgM, high affinity [Source:MGI Symbol;Acc:MGI:1927803] |
| Ensembl ID | ENSMUSG00000026415 |
| Bio databases IDs | |
| Aliases | Fc receptor, IgA, IgM, high affinity |
| Synonyms | CD351, Fc alpha and mu receptor, FCALPHA / FCMU receptor, Fcalpha/muR, FCA/MR, Fc receptor, IgA, IgM, high affinity, Fc α and mu receptor, Fc α/mu r, FKSG87, LOC681814 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fcamr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin V-Type
- immunoglobulin domain
- Immunoglobulin like
- IgA binding
- immunoglobulin binding
- transmembrane receptor
- Immunoglobulin V-set domain
Pathways
Biological processes and signaling networks where the Fcamr gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fcamr gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- adaptive immune response
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane signaling receptor activity