GALNTL6 Gene Summary [Human]
Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GALNTL6 |
| Official Name | polypeptide N-acetylgalactosaminyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:33844] |
| Ensembl ID | ENSG00000174473 |
| Bio databases IDs | |
| Aliases | polypeptide N-acetylgalactosaminyltransferase like 6, polypeptide GalNAc transferase-like 6 |
| Synonyms | 1700021K10RIK, 4930431L04Rik, A830023L05, GALNACT20, GalNAc-T6L, GALNT17, polypeptide N-acetylgalactosaminyltransferase-like 6, RGD1564773, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6, UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GALNTL6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ricin-type beta-trefoil lectin domain
- Glycosyl transferase family 2
- Ricin-type beta-trefoil
- polypeptide N-acetylgalactosaminyltransferase
- N-terminal domain of galactosyltransferase
- beta-trefoil_Ricin_MRC-like
- enzyme
- ricin B-type lectin domain, beta-trefoil fold
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GALNTL6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
- protein O-linked glycosylation via threonine
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- carbohydrate binding
- polypeptide N-acetylgalactosaminyltransferase activity