CBLL2 Gene Summary [Human]
This gene encodes a member of the zinc finger domain-containing protein family. This family member contains both a RING-type and a C2H2-type of zinc finger domain, and it may function as an E3 ubiquitin-protein ligase. Protein localization suggests a role in human sperm production and quality control. [provided by RefSeq, Aug 2011]
Details
| Type | Protein Coding |
| Official Symbol | CBLL2 |
| Official Name | Cbl proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:26371] |
| Ensembl ID | ENSG00000175809 |
| Bio databases IDs | |
| Aliases | Cbl proto-oncogene like 2 |
| Synonyms | Cbl proto-oncogene like 2, CT138, HAKAIL, ZNF645 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CBLL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C2H2 Hakai zinc finger domain
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- protein binding
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CBLL2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell adhesion
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding