PIH1D2 Gene Summary [Human]

Enables small GTPase binding activity. Predicted to be involved in box C/D snoRNP assembly and rRNA processing. Predicted to be part of R2TP complex and ribonucleoprotein complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PIH1D2
Official Name
PIH1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25210]
Ensembl ID
ENSG00000150773
Bio databases IDs NCBI: 120379 Ensembl: ENSG00000150773
Aliases PIH1 domain containing 2, dynein axonemal assembly factor 15
Synonyms 2700059L22Rik, DNAAF15, PIH1 domain containing 2, RGD1310503
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PIH1D2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PIH1 CS-like domain
  • HSP20-like domain found in ArsA
  • alpha-crystallin Hsps/p23-like
  • enzyme binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PIH1D2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • box C/D snoRNP assembly
  • rRNA processing
  • protein stabilization

Cellular Component

Where in the cell the gene product is active
  • R2TP complex
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.