THAP4 Gene Summary [Human]
Enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Involved in nitrate metabolic process and tyrosine metabolic process. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | THAP4 |
| Official Name | THAP domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23187] |
| Ensembl ID | ENSG00000176946 |
| Bio databases IDs | |
| Aliases | THAP domain containing 4, nitrobindin |
| Synonyms | 2010320B01RIK, CGI-36, Nb(III), PP238, THAP domain containing 4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human THAP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- THAP4-like, heme-binding beta-barrel domain
- binding protein
- lipocalin/cytosolic fatty acid-binding protein family
- THAP domain
- isomerase
- protein binding
- heme binding
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human THAP4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tyrosine metabolic process
- nitrate metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- identical protein binding
- protein binding
- metal ion binding
- nitric oxide binding
- heme binding