Thap4 Gene Summary [Mouse]
Predicted to enable several functions, including heme binding activity; nitric oxide binding activity; and peroxynitrite isomerase activity. Predicted to be involved in nitrate metabolic process and tyrosine metabolic process. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina nuclear layer; and submandibular gland primordium. Orthologous to human THAP4 (THAP domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Thap4 |
| Official Name | THAP domain containing 4 [Source:MGI Symbol;Acc:MGI:1914276] |
| Ensembl ID | ENSMUSG00000026279 |
| Bio databases IDs | |
| Aliases | THAP domain containing 4 |
| Synonyms | 2010320B01RIK, CGI-36, Nb(III), PP238, THAP domain containing 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Thap4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- THAP4-like, heme-binding beta-barrel domain
- binding protein
- lipocalin/cytosolic fatty acid-binding protein family
- THAP domain
- isomerase
- protein binding
- heme binding
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Thap4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tyrosine metabolic process
- nitrate metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- identical protein binding
- protein binding
- metal ion binding
- nitric oxide binding
- heme binding