MRGPRX3 Gene Summary [Human]
This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]
Details
| Type | Protein Coding |
| Official Symbol | MRGPRX3 |
| Official Name | MAS related GPR family member X3 [Source:HGNC Symbol;Acc:HGNC:17980] |
| Ensembl ID | ENSG00000179826 |
| Bio databases IDs | |
| Aliases | MAS related GPR family member X3 |
| Synonyms | GPCR, MAS related GPR family member X3, MRGA10, MRGX3, SNSR1, SNSR2 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MRGPRX3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MRGPRX3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding