NME9 Gene Summary [Human]

Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in dynein axonemal particle. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
NME9
Official Name
NME/NM23 family member 9 [Source:HGNC Symbol;Acc:HGNC:21343]
Ensembl ID
ENSG00000181322
Bio databases IDs NCBI: 347736 Ensembl: ENSG00000181322
Aliases NME/NM23 family member 9
Synonyms NM23-H9, NME/NM23 family member 9, NXL2, RGD1564871, TXL-2, TXNDC6
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NME9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • nucleoside diphosphate kinase
  • Nucleoside diphosphate kinase family
  • NDPk
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • enzyme
  • thioredoxin

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • Alzheimer disease
  • amyotrophic lateral sclerosis
regulated by
role in cell
  • invasion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • organelle
  • microtubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human NME9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • UTP biosynthetic process
  • CTP biosynthetic process
  • GTP biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • cell projection

Molecular Function

What the gene product does at the molecular level
  • nucleoside diphosphate kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.