CALHM3 Gene Summary [Human]
Predicted to enable cation channel activity. Predicted to be involved in ATP transport. Predicted to be located in basolateral plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CALHM3 |
| Official Name | calcium homeostasis modulator 3 [Source:HGNC Symbol;Acc:HGNC:23458] |
| Ensembl ID | ENSG00000183128 |
| Bio databases IDs | |
| Aliases | calcium homeostasis modulator 3 |
| Synonyms | bA225H22.7, calcium homeostasis modulator 3, FAM26A, RGD1560215 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CALHM3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcium homeostasis modulator
- channel/pore class transporter
- protein binding
- voltage-gated ion channel
- ion channel
Pathways
Biological processes and signaling networks where the CALHM3 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- basolateral membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CALHM3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of taste
- calcium ion transmembrane transport
- protein heterooligomerization
- ATP transport
Cellular Component
Where in the cell the gene product is active
- basolateral plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium channel activity
- cation channel activity
- voltage-gated ion channel activity