IGFL1 Gene Summary [Human]
The protein encoded by this gene is a member of the insulin-like growth factor family of signaling molecules. The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. The mature peptide binds to a receptor, which in mouse was found on the cell surface of T cells. Increased expression of this gene may be linked to psoriasis. [provided by RefSeq, Aug 2016]
Details
| Type | Protein Coding |
| Official Symbol | IGFL1 |
| Official Name | IGF like family member 1 [Source:HGNC Symbol;Acc:HGNC:24093] |
| Ensembl ID | ENSG00000188293 |
| Bio databases IDs | |
| Aliases | IGF like family member 1 |
| Synonyms | APRG644, IGF like family member 1, UNQ644 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGFL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IGFL1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- protein binding
- receptor binding