C6orf89 Gene Summary [Human]

Involved in several processes, including epithelial cell proliferation; positive regulation of histone deacetylase activity; and wound healing. Located in several cellular components, including Golgi membrane; midbody; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
C6orf89
Official Name
chromosome 6 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:21114]
Ensembl ID
ENSG00000198663
Bio databases IDs NCBI: 221477 Ensembl: ENSG00000198663
Aliases chromosome 6 open reading frame 89, bombesin receptor activated protein, amfion
Synonyms 2400006G15Rik, BC004004, BRAP, C20h6orf89, cDNA sequence BC004004, chromosome 6 open reading frame 89, PS1TP5TP1, RGD735065, similar to human chromosome 6 open reading frame 89
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C6orf89 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dermatitis
regulated by
regulates
role in cell
  • proliferation
  • cell cycle progression
  • autophagy by
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • midbody
  • Golgi membrane
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human C6orf89 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • wound healing
  • chromatin remodeling
  • epithelial cell proliferation
  • positive regulation of cell cycle

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • Golgi membrane
  • midbody
  • nucleolus
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.