ASAH2B Gene Summary [Human]

Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in ceramide catabolic process; long-chain fatty acid biosynthetic process; and sphingosine biosynthetic process. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ASAH2B
Official Name
N-acylsphingosine amidohydrolase 2B [Source:HGNC Symbol;Acc:HGNC:23456]
Ensembl ID
ENSG00000204147
Bio databases IDs NCBI: 653308 Ensembl: ENSG00000204147
Aliases N-acylsphingosine amidohydrolase 2B
Synonyms ASAH2C, ASAH2L, bA449O16.3, bA98I6.3, N-acylsphingosine amidohydrolase 2B
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ASAH2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Neutral/alkaline non-lysosomal ceramidase, C-terminal

Pathways

Biological processes and signaling networks where the ASAH2B gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • RIGI

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ASAH2B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ceramide catabolic process

Molecular Function

What the gene product does at the molecular level
  • ceramidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.