MZT1 Gene Summary [Human]
Involved in gamma-tubulin complex localization. Located in centrosome and spindle. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MZT1 |
| Official Name | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] |
| Ensembl ID | ENSG00000204899 |
| Bio databases IDs | |
| Aliases | mitotic spindle organizing protein 1, mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1 |
| Synonyms | 2410129H14Rik, C13orf37, FLJ21869, mitotic spindle organizing protein 1, MOZART1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MZT1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic-spindle organizing gamma-tubulin ring associated
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- spindle apparatus
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MZT1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- gamma-tubulin complex localization
- interphase microtubule nucleation by interphase microtubule organizing center
- spindle assembly involved in mitosis
Cellular Component
Where in the cell the gene product is active
- centrosome
- interphase microtubule organizing center
- spindle
- cytosol
- gamma-tubulin large complex
- gamma-tubulin complex
Molecular Function
What the gene product does at the molecular level
- protein binding