SLC35B4 Gene Summary [Human]
Glycosyltransferases, such as SLC35B4, transport nucleotide sugars from the cytoplasm where they are synthesized, to the Golgi apparatus where they are utilized in the synthesis of glycoproteins, glycolipids, and proteoglycans (Ashikov et al., 2005 [PubMed 15911612]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | SLC35B4 |
| Official Name | solute carrier family 35 member B4 [Source:HGNC Symbol;Acc:HGNC:20584] |
| Ensembl ID | ENSG00000205060 |
| Bio databases IDs | |
| Aliases | solute carrier family 35 member B4 |
| Synonyms | 4930474D06Rik, AB041549, AW494345, Slc35b4 predicted, solute carrier family 35 member B4, solute carrier family 35, member B4, YEA, YEA4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC35B4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-xylose transporter
- Triose-phosphate Transporter family
- UAA transporter family
- EamA-like transporter family
- UDP-N-acetylglucosamine transporter
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Endoplasmic Reticulum
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC35B4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- UDP-xylose transport
- regulation of gluconeogenesis
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- Golgi apparatus
- Golgi membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- UDP-N-acetylglucosamine transmembrane transporter activity
- UDP-xylose transmembrane transporter activity