Slc35b4 Gene Summary [Mouse]

Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Acts upstream of or within regulation of gluconeogenesis. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SLC35B4 (solute carrier family 35 member B4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc35b4
Official Name
solute carrier family 35, member B4 [Source:MGI Symbol;Acc:MGI:1931249]
Ensembl ID
ENSMUSG00000018999
Bio databases IDs NCBI: 58246 Ensembl: ENSMUSG00000018999
Aliases solute carrier family 35, member B4
Synonyms 4930474D06Rik, AB041549, AW494345, Slc35b4 predicted, solute carrier family 35 member B4, solute carrier family 35, member B4, YEA, YEA4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc35b4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UDP-xylose transporter
  • Triose-phosphate Transporter family
  • UAA transporter family
  • EamA-like transporter family
  • UDP-N-acetylglucosamine transporter
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
regulated by
regulates
  • UDP-D-xylose
  • UDP-N-acetylglucosamine
role in cell
  • gluconeogenesis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc35b4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • UDP-xylose transport
  • regulation of gluconeogenesis

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • Golgi apparatus
  • Golgi membrane
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • UDP-N-acetylglucosamine transmembrane transporter activity
  • UDP-xylose transmembrane transporter activity