CRYZL1 Gene Summary [Human]

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
CRYZL1
Official Name
crystallin zeta like 1 [Source:HGNC Symbol;Acc:HGNC:2420]
Ensembl ID
ENSG00000205758
Bio databases IDs NCBI: 9946 Ensembl: ENSG00000205758
Aliases crystallin zeta like 1, quinone reductase-like 1
Synonyms 2210407J23Rik, 2410006O11Rik, 4P11, crystallin zeta like 1, crystallin ζ like 1, FERRY4, Fy-4, QOH-1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CRYZL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • MDR
  • enzyme
  • protein binding
  • identical protein binding
  • Enoylreductase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • Crohn disease
regulated by
  • sulforafan

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • early endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CRYZL1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • NADP binding
  • protein binding
  • NADPH:quinone reductase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.