TRGV8 Gene Summary [Human]
Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | T-Cell Receptor Variable Gene |
| Official Symbol | TRGV8 |
| Official Name | T cell receptor gamma variable 8 [Source:HGNC Symbol;Acc:HGNC:12294] |
| Ensembl ID | ENSG00000211696 |
| Bio databases IDs | |
| Aliases | T cell receptor gamma variable 8, T-cell receptor, gamma, variable region V8 |
| Synonyms | T cell receptor gamma variable 8, T cell receptor γ variable 8, TCRGV8, V1S8, Vgamma8 |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the TRGV8 gene in human plays a role, providing insight into its function and relevance in health or disease.
- Allograft Rejection Signaling
- Antiproliferative Role of TOB in T Cell Signaling
- Autoimmune Thyroid Disease Signaling
- Calcium-induced T Lymphocyte Apoptosis
- CCR5 Signaling in Macrophages
- Cdc42 Signaling
- CTLA4 Signaling in Cytotoxic T Lymphocytes
- Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells
- Dendritic Cell Maturation
- G Protein Signaling Mediated by Tubby
- Graft-versus-Host Disease Signaling
- IL-4 Signaling
- Lipid Antigen Presentation by CD1
- NF-κB Signaling
- Nur77 Signaling in T Lymphocytes
- OX40 Signaling Pathway
- PKCθ Signaling in T Lymphocytes
- SAPK/JNK Signaling
- T Cell Receptor Signaling
- TEC Kinase Signaling
- Th17 Activation Pathway
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRGV8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- adaptive immune response
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- T cell receptor complex